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ALOES. VEGETABLE PURGATIVES The solid residue obtained by evaporating the liquid which drains fromthe cut leaves of various species of Aloe (Liliaceae) it is known in commerce as Cape or Curacao (Barbados) aloes. It contains barbaloin, a yellow crystalline glycoside. Foreign Pharmacopeias: In all pharmacopeias examined except Chin. and Mex. U.S. allows also Socotrine aloes. Cape aloes occurs in dark brown, or greenish brown, glassy masses, thin fragments of which are transparent and exhibit a yellowish, reddish-brown, or greenish tinge; it breaks with a clean glassy fracture and has a distinctive, somewhat acid odour. Curacao aloes occurs as dark, chocolate-brown, opaque masses with a dull waxy fracture; it has a characteristic penetrating odour. Socotrine aloes occurs as nearly black opaque masses with an uneven porous fracture and an unpleasant cheesy odour. Zanzibar aloes occurs as livery-brown masses with a nearly smooth slightly porous fracture and a slight odour. Cape and Curacao aloes are almost entirely soluble in alcohol (60%). Uses. Aloes is a cathartic producing a motion 6 to 12 hours after administration. As it is intensely bitter it is usually given in pills or tablets. Moderate doses are laxative but owing to their tendency to cause griping they are commonly combined with belladonna or carminatives. Since aloes does not lose its efficacy on continued use it is a useful medicament in the treatment of chronic constipation. The action of aloes on the large intestine causes some pelvic congestion and it should not be used by pregnant or nursing women, or where there is intestinal irritation. Dec. Aloes Co. Conc. (B.P.C. 1949). Concentrated Compound Decoction of Aloes. Prepared from aloes 40 g., myrrh 20 g., potassium carbonate 20 g., extract of liquorice 160 g., cochineal 12 g. cardamom seed 15 g.,cinnamon oil 0.3 mI., caraway oil 0.4 mI., alcohol (90%) 150 ml., water to 1000 ml. Diluted with 3 times its volume of water, it yields a preparation approximately equivalent in strength to compound decoction of aloes but contains a smaller proportion of alcohol. Extract Pills Pil. Aloes et Asafoet. (B.P.C. 1949). Pills of Aloes and Asafetida. Aloes, asafetida, and hard soap, of each; 1/6 gr . massed with syrup of liquid glucose. Pil. Aloes et Ferr. (B.P.C. 1949). Pills of Aloes and Iron. Aloes 4/5 gr exsiccated ferrous sulphate 2/5 gr., cinnamon 1/2 gr., cardamom seed 1/2 gr., and ginger ? gr massed with syrup of liquid glucose. Pil. Aloes et Myrrh. (B.P.C. 1949). Pills of Aloes and Myrrh; pit. Rufi; Rufus Pills. Aloes 2 gr. and myrrh 1 gr., massed with syrup of liquid glucose. Pills of Aloes and Nux Vomica (B.P.C., N.F. 1952). Pil. Aloes et Nuc.Vom. Aloes 2 gr., dry extract of nux vomica 1/4 gr., and dry extract of belladonna 1/6gr. Powder
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Aloes.sp.