The National Formulary
U.S.D. 21st Edition 1926.

A to D
Edited by
Ivor Hughes

The National Formulary, published  by the American Pharmaceutical Association, was originally planned as a convenience for druggists by providing them with standardized.formulas. for preparations called for either by the laity or by physicians. Under the Federal law of 1906 it became a legal standard for medicines in the United States. This change in its status has led to some modification in the character of the N.F. it has been divided in two parts: first a collection of formulas of the same type as originally composed the book, and second a description of such crude drugs employed in these formulas as are not recognized by the Pharmacopoeia, with tests for their quality. This second part of the N.F. being essentially of the same category as the Pharmacopeia descriptions, has been included in Part 1 of the present work. The Galenicals of the N, F., being of less importance, are given only in abstract in this place.

ACETUM AROMATICUM. N.F.
Aromatic Vinegar [Acet. Arom.] It contains the volatile oils of lavender, rosemary, juniper, peppermint, cinnamon, lemon and clove, dissolved in alcohol, acetic acid and water, and is used as a stimulating inhalant.

ACIDUM NITROHYDROCHLORICUM. N.F.
Nitrohydrochloric Acid [Acid. Nitrohydrochl.] Nitromuriatic Acid; Aqua Regia.
This differs materially from the acid of, the same name which is official in the Br. It is made by mixing eighteen parts of nitric acid, eighty two parts of hydrochloric acid.

It is a golden yellow, fuming liquid with a chlorinous odor; it becomes lighter in color when kept, but only the golden fluid should be dispensed. The N. F. directs that unless it immediately liberates iodine from aqeous solution of potassium iodide it should not be dispensed. For description of chemical and therapeutic properties see Acidum Nitrohydrochloricum, Part I.
Dose, three to five minims (0.2-0.3 cc.). 

ACIDUM NITROHYDROCHLORICUM DILUTUM. N.F. 
Diluted Nitrohydrochloric Acid [Acid. Nitrohydrochl. Dil.] Diluted Nitromuriatic Acid.
This represents approximately 22 per cent. of the nitrohydrochloric acid, N; F .
Dose, fifteen to thirty minims (1-2 cc. )      

AMPULLAE
Ampules
These are small, hermetically sealed containers which are filled with a sterile solution of a medicinal agent intended for hypodermic injection. In our opinion the name is an unfortunate one as it applies to the container rather than the contents; the British name, for the corresponding preparation, of injectiones Hypodermicoe seems more appropriate.

The amount of solution in each is a little more than 1 cc. (except one which is 2 cc.) this is to allow for the small amount of liquid which inevitably remains in the container when the physician fill's his syringe from it.

AMPULLAE CAFFEINAE SODIO BENZOATIS. N.F.
Ampules of Caffeine Sodio-Benzoate [Ampul. Caf. Sod.-Benz.]
Each ampule represents 0.5 Gm. (eight grains) of the USP caffeine sodio-benzoate in sterile distilled water.
Dose, one ampule.

AMPULLAE CAMPHORAE.
Ampules of Camphor
Each ampule contains 0.2 Gm. (three grains) of camphor dissolved in cottonseed oil. It is used as a circulatory stimulant.
Dose, one ampule. 

AMPULLAE  EMETINAE  HYDROCHLORIDI N.F.
Ampules of Emetine Hydrochloride [Ampul. Emet. Hydrochl.]
Each ampule contains 0.03 Gm. ( one-half grain) of emetine hydrochloride, It is used in the treatment of dysentery.
Dose, one ampule.

AMPULLAE  IODl. N.F.
Ampules of Iodine, Iodine Swabs.
This is a solution of 3.5 per cent. of iodine and 2.5 per cent. of potassium iodide, in 70 per cent. alcohol. It is intended as a surgical antiseptic, being of a more desirable strength for this purpose than the U.S. tincture of iodine.    

AMPULLAE QUININAE ET UREAE  HYDROCHLORIDI. N. F. 
Ampules of Quinine and Urea Hydrochloride [Ampul. Quin. Et Urea Hydrochl.] 
Each contains 0.5 Gm. of quinine and urea, hydrochloride., It affords a convenient method of obtaining the therapeutic action of quinine by hypodermic injection and is especially employed in pneumonia.
Dose, one ampule.  

AMPULLAE QUININAE DIHYDROCHLORIDI. N.F.
Ampules of Quinine Dihydrochloride [Ampul.Quin. Dihydrochl.] 
Each ampule contains 0,5 Gm.of the acid hydrochloride of quinine, the acidity of the solvent being regulated by titration. It is intended for the hypodermic administration of quinine, especially in severe cases of malarial fever.
Dose, one ampule. 

AMPULLAE SODII CACODYLATIS. N.F.
Ampules of Sodium Cacodylate [Ampul. Sod. Cacodyl.]
Each ampule contains 0.3 Gm. (five grains) of sodinm cacodylate.
Dose, one ampule. 

AQUA HAMAMELIDIS; N.F
Hamamelis Water [Aq. Hamam.] Witch Hazel Water.
This is a popular, but useless, embrocation made by distillation of Hamamelis twigs It contains a trace of volatile oil but no therapeutically active substance; even the alcohol present is in too small a proportion to exert any beneficial action. 

AQUA PHENOLATA. N.F. 
Phenolated Water [Aq. Phenol.] Carbolic Acid Water; Phenolis Soluto, P. I.
This is a 2 per cent. solution of phenol in distilled water and is, used as a lotion, gargle, etc.   

CAFFEINAE SODIO-SALICYLAS. N.F.
Caffeine Sodio-Salicylate [Caff. Sod.-Sal.]
This powder .contains equal parts of caffeine and sodium salicylate. It is used for the same purposes as the caffeine sodio-benzoate (see Part 1)
Dose is three grains {0.2 Gm.).  

CATAPLASMA KAOLINI. N.F.
Cataplasm of Kaolin [Catapl. Kaolin.]
This is a mixture of kaolin, glycerin, borIc acid, thymol and oils of peppermint and wintergreen. It is used as a substitute for poultices. It should be applied as hot as can be comfortably endured.

CERATUM CAMPHORAE. N.F.
Camphor Cerate [Cerat. Camph.] Camphorated Ointment.
This preparation is composed of 10 per cent. of camphor liniment in a cerate base.  

CERATUM PLUMBI SUBACETATIS. N. F.
Cerate of Lead Subacetate [Cerat. Plumb. Subacet.] Goulard's Cerate.
This well-known cerate contains 20 per cent. of Goulard's extract mixed with a cerate base containing a little camphor. It is used as an astringent and sedative dressing.  

CERATUM RESINAE COMPOSITUM. N.F.
Compound Rosin Cerate [Cerat. Resin. Co.] Deshler's Salve.
This popular cerate contains rosin, yellow wax, suet, turpentine, and linseed oil. It is used as a stimulating dressing.  

CHARTA POTASSII NITRATIS. N.F.
Potassium Nitrate Paper [Chart. Pot. Nit.]
This is made by saturating unsized paper in a strong solution of potassium nitrate and drying. It is used in asthma .by burning it and inhaling the smoke. 

CHLORAL CAMPHORATUM. N.F.  
Camphorated Chloral [Chloral Camph.]
A eutectic mixture of equal parts of hydrated chloral and camphor, used as a local anodyne and, counter irritant. 
 
COLLODIUM BITUMINIS SULPHONATI. N.F.
Collodion of Sulphonated Bitumen [Collod. Bitum. Sulphon.] Ichthyol Collodion.
This contains 10 per cent. of sulphonated bitumen in flexible collodion. It does not seem to us a very efflcient way of applying ichthyol.     

COLLODIUM SALICYLICUM COMPOSITUM. N.F.
Compound Salicylic Collodion [Collod. Sal. Co.] Corn Collodion;
Collodium Salicylatum Compositum.
It contains salicylic acid, extract of cannabis, and flexible collodion. Used for the removal of corns. 

COLLODIUM STYPTICUM. N.F.
Styptic Collodion [Collod. Stypt.]
This is a 20 per cent., by weight, solution of tannic acid in flexible collodion. It is used as a styptic application to cuts and small wounds.

CONFECTIO ROSAE N.F.
Confection of Rose [Confect. Ros.]
It is used principally as a pill excipient or vehicle.
(See Confectio Rosa Gallicae. Part 1.) 

CONFECTIO SENNAE N.F.
Confection of Senna [Confect. Senn.]
This is very 'similar to the Br. confection of senna (see Part 1)
Dose, sixty grains, 4 Gill., representing six grains of senna and nine and a half grains of cassia fistula.   

CURATIO PARAFFINI. N.F.
Paraffin Dressing [Curat. Paraf.] Paraffin Film.
Under this peculiar title is a paraffin softened by the addition of white petrolatum and olive oil, and containing 1 per cent. of resorcinol and 2 per cent. of eucalyptol. It is intended as a local application for burns.   

DENTIFRICIUM. N.F.
Dentifrice [Dentif.]Tooth-powder; Oxidizing Tooth-powder;
This tooth-powder contains soap, sugar and flavoring, prepared chalk, precipitated calcium carbonate and 5 per cent. of sodium perborate ; because of the abrasive properties of precipitated calcium carbonate it would have been better, in our opinion, to have substituted for it an increase in the amount of chalk..   

DENTlLINIMENTUM ACONITI COMPOSITUM. N.F.
Compound Dental Liniment of Aconite [Dentilin. Aconit. Co.]
This contains 36 per cent. of menthol and 13.5per cent. of chloroform in tincture of aconite. It is a powerful counter-irritant and local anesthetic used in neuralgic conditions of the gums and in toothache. It should not be confounded with the compound liniment of aconite which is used externally.   

DENTILINIMENTUM ACONITI ET IODI COMPOSITUM. N. F.
Compound Dental Liniment of Aconite and Iodine [Dentilin. Aconit. et lod. Co.]
Refrigerant Counter-irritant. This contains 2.2 per cent. of each of menthol and iodine and 16.5 per cent. of chloroform dissolved in tincture of aconite. It is used for similar properties to the above but is less actively counter-irritant but more antiseptic.

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